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Dr. Joachim Ix and Coworkers Find Link Between Liver Protein and Type 2 Diabetes
A research team led by Dr. Joachim H. Ix has found that individuals who have higher levels of a particular liver protein are at a greater risk for developing Type 2 diabetes. Dr. Joachim H. Ix, M.D.,...
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Drs. Wang and Kolodner Find a Key to Cisplatin Resistance
Why are some patients resistant to cisplatin chemotherapy for cancer? A clue has come from a study released this month by Drs. Jean Wang, Richard Kolodner, and colleagues. In patients who receive...
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Macrophage Protein Has Major Role in Inflammation
Researchers at the University of California, San Diego School of Medicine have discovered that a multi-tasking protein called FoxO1 has another important but previously unknown function: It directly...
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Powerful Approach to the Analysis of Protein Motions
DXMS analysis provides novel tool for studying how movements allow proteins to perform their functions as molecular machines Researchers at the University of California, San Diego School of Medicine...
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Knocking Out Key Protein in Mice Boosts Insulin Sensitivity
By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically...
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Insulin Resistance, Inflammation and a Muscle-Saving Protein
In the online May 2 issue of the journal Cell Metabolism, researchers at the University of California, San Diego School of Medicine publish three distinct articles exploring: the complex interactions...
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Enzyme Offers New Therapeutic Target for Cancer Drugs
Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process...
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Cholesterol Sets Off Chaotic Blood Vessel Growth
A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from...
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Developmental Protein Plays Role in Spread of Cancer
A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report...
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The Connection Between Oxygen and Diabetes
A lack of O2 in fat cells triggers inflammation and insulin resistance in obesity: Researchers at the University of California, San Diego School of Medicine have, for the first time, described the...
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